Ma Laboratory

I am an associate professor of Department of Electronic Engineering and Institute for AI Industry Research at Tsinghua University. Before joining Tsinghua University, I was a tenure track Walther Assistant Professor of Department of Computer Science and Department of Biochemistry at Purdue University Email: majianzhu <at> tsinghua <dot> edu <dot> cn My wife's homepage.

Notice: For students in Tsinghua University, please contact me if you are interested in workinig with me.
I am looking for talanted Master students, Ph.D. students to work with in the following directions,

• Graphical Neural Network, Deep Learning

• Immunology, Drug Discovery

• Bioinformatics and Computational Biology

For undergraduate and master studuents, please don't do the following: First contact me to do research and then tell me you need to focus on your homework and final.

Selected Publications

Large Scale Foundation Model on Single-cell Transcriptomics
Minsheng Hao, Jing Gong, Xin Zeng, Chiming Liu, Yucheng Guo, Xingyi Cheng, Taifeng Wang, Jianzhu Ma, Xuegong Zhang, Le Song
Nature Methods 2024 corresponding author

High-resolution de novo structure prediction from primary sequence
Ruidong Wu, Fan Ding, Rui Wang, Rui Shen, Xiwen Zhang, Shitong Luo, Chenpeng Su, Zuofan Wu, Qi Xie, Bonnie Berger, Jianzhu Ma, Jian Peng
bioRxiv 2022 corresponding author

• AI BUSINESS: DeepMind challenger? A ‘super fast' protein predicting model
  

• News Medicial Life Science: Revolutionizing protein design: AI generates novel sequences
  

• Analytics Drift: Top 5 protein folding models
  

Quantifying spatial homogeneity of urban road networks via graph neural networks
Jiawei Xue, Nan Jiang, Senwei Liang, Qiyuan Pang, Takahiro Yabe, Satish Ukkusuri, Jianzhu Ma
Nature Machine Intelligence 2022 cover paper

• TechExplore: Using graph neural networks to measure the spatial homogeneity of road networks
  

• Nature Computational Science: Gauging urban development with neural networks
  

Few-shot learning creates predictive models of drug response that translate from high-throughput screens to individual patients
Jianzhu Ma, Samson Fong, Yunan Luo, Christopher Bakkenist, John Paul Shen, Soufiane Mourragui, Lodewyk Wessels, Marc Hafner, Roded Sharan, Jian Peng, Trey Ideker
Nature Cancer 2020

Predicting drug response and synergy using a deep learning model of a cancer cell
Brent Kuenzi, Jisoo Park, Samson H. Fong, Kyle Salinas Sanchez, Jason F. Kreisberg, Jianzhu Ma, Trey Ideker
Cancer Cell 2020

• ScienceDaily: DrugCell: New experimental AI platform matches tumor to best drug combo
  

• Health IT Analytics: Deep Learning Model Could Enhance Cancer Precision Medicine
  

• Med India: New AI Platform Matches Tumor to Right Drug Combination

• AZO Life Sciences: Experimental AI platform predicts best approach to cancer treatment

• UC San Diego Health Newsroom: DrugCell: New Experimental AI Platform Matches Tumor to Best Drug Combo

Using deep learning to model the hierarchical structure and function of a cell
Jianzhu Ma, Michael Ku Yu, Samson Fong, Keiichiro Ono, Eric Sage, Barry Demchak, Roded Sharan, Trey Ideker
Nature Methods 2018

• Cover Art: Nature Methods About the Cover: April 2018 Vol 15 No 4
  

• IEEE SPECTRUM: Cracking Open the Black Box of AI with Cell Biology
  

• UCSD Health: How a Yeast Cell Helps Crack Open the “Black Box” Behind Artificial Intelligence
  

• GenomeWeb: Deep Learning-Based Cell Model May Predict Patient Tumor Cell Growth Someday
  

• Nature: Deep learning takes on tumours
  

A conserved epigenetic progression aligns dog and human age
Tina Wang, Jianzhu Ma, Andrew N. Hogan, Samson Fong, Katherine Licon, Brian Tsui, Jason F. Kreisberg, Peter D. Adams,
Anne-Ruxandra Carvunis, Danika L. Bannasch, Elaine A. Ostrander and Trey Ideker
Cell Systems 2020

• NPR A New Way To Calculate Your Dog's Age

• ABC New way to calculate dogs’ ages may unlock secret to aging

• NBC Forget ‘Dog Years’: Scientists Say We've Been Calculating Our Pups’ Ages Wrong

• Scientific American Podcast: How old is your dog in human years? Genetic study offers a new way to answer that question.

• BBC future How to calculate your dog's real age

• Nature Briefing Daily briefing: A better formula for ‘dog years’.

• Science News Here’s a better way to convert dog years to human years, scientists say.

• Wall Street Journal Our Problem With Percentages.

• Washington Post Scientists have come up with a better way to convert your dog’s age to human years.

• New Scientist Convert your dog’s age into human years using this new formula.

• Discover Science May Have a Better Way to Translate Dog Years to Human Years.

• New York Magazine, The Cut There’s a New Way to Calculate Your Dog’s Age in Human Years.

• New York Post Why a dog’s age in ‘human years’ might not be as old as you think.

• People Magazine There’s a Better Way Calculate Your Dog’s True Age in Dog Years, Researchers Say.

• The Sun, also Fox news Your dog’s REAL age in ‘dog years’ revealed (and it’s not their age multiplied by seven).

• The Scientist Magazine Ribosomal DNA Can Predict an Animal’s Age.

• Science Alert What’s The Real Human Equivalent of Your Dog’s Age? Here’s a New Formula.

• Smart News Calculate Your Dog’s Age With This New, Improved Formula.

• Gigazine A new formula for converting the age of dogs to humans has appeared, how old are 1-year-old dogs?

• Considerable There’s a new way to calculate your dog’s age in human years.

• Techballad New “dog to human years” calculation more accurately determines when your beloved pet will die.

• Daily Mail How old is your dog REALLY in 'human years’? Researchers come up with a new formula for calculating the 'true age’ of your canine friend (and it's not multiplying it by seven).

• Green Report Una nuova formula matematica per calcolare l’età “umana” dei cani.

• eestinen Kui vana on koer tegelikult inimese aastates – ja see ei ole nii lihtne nagu 7-ga korrutamine!

• hani 사람 나이론 42살’ 2살 강아지, ‘폭풍 성장’ 비밀 밝혀져.

• Nedd Lidský rok = sedm psích let. Rovnice, která neplatí.

• gurumed La véritable formule pour calculer l’équivalent en âge humain de votre chien.

• IT 뉴스 개 나이 인간 나이 환산 새로운 공식 나왔다.

• skuola Quanti anni ha il tuo cane? La nuova formula per capirlo.

• BioWorld 狗活一年相当于人活30年？研究人员发明了计算公式，并开发了一个换算计算器。

• wonderfulnews 犬の年齢で衝撃データ!? 人間に換算する新しい公式が登場「16×loge(犬の年齢)＋31＝人間に換算した年齢」